R. Malothu Genome, editing, gene, poor, countries 11-11 Volume 1 (1) January, 2025 Genome editingand#39;s necessity depends on the application: itand#39;s seen as highly necessary and beneficial for treating diseases in existing individuals (somatic editing, like CAR-T cancer therapy) and improving crops, but itand#39;s currently considered ethically problematic and premature for heritable changes (germline editing) due to safety, long-term consequences, and societal concerns, with international calls for caution and regulation. Genome editing is considered necessary and highly beneficial for poor countries, particularly for enhancing food security, nutrition, and public health. International bodies like the World Health Organization (WHO) urge for equitable access to this technology, arguing that it is not ethically or scientifically justifiable to leave less-resourced countries behind.