L. Sampath, S. Kumar, N. Naidu Genome, Geneme editing, IPR, issues, scenario 50-53 Volume 1 (5) September, 2025 Genome editing raises intellectual property (IP) issues primarily related to patenting, which can lead to corporate control, high costs, and potential monopolies over essential technologies, potentially hindering access for farmers and researchers. Complex patent thickets around tools like CRISPR can also create legal hurdles, increasing costs and slowing down innovation and application. Balancing the need to reward inventors with the goal of open innovation and equitable access to these vital technologies for global challenges like food security and health is a key challenge.